Continuing a nearly 50-year-old tradition of honoring outstanding achievement in cancer research, the American Association for Cancer Research currently is accepting nominations for its series of annual awards. Scientists advancing the understanding and eradication of cancer through basic research, clinical care, therapeutics and prevention are eligible. Winners will help the AACR fulfill its mission to promote professional education and communications by delivering a lecture during the AACR’s Centennial Year Annual Meeting, April 14-18, 2007, in Los Angeles, Calif. The fields and corresponding awards represented are: Basic cancer research: AACR–G.H.A. Clowes Memorial Award, in honor of a founding member of the AACR and a research director at the Eli Lilly Company. Improved clinical cancer care: AACR–Richard and Hinda Rosenthal Foundation Award, which recognizes notable contributions on the part of medical practitioners aged 50 or younger who reside in the Americas, and provides incentives to young investigators relatively early in their careers. Clinical cancer research: AACR–Joseph H. Burchenal Clinical Research Award, recognizes outstanding achievements in clinical cancer research. It is named for Dr. Joseph H. Burchenal, Past President of the AACR, and a major figure in clinical cancer research and chemotherapy. Meritorious achievement by a young investigator: AACR Award for Outstanding Achievement in Cancer Research, to give recognition to a young investigator (not more than 40 years of age) on the basis of meritorious achievement in cancer research. Epidemiology, biomarkers and prevention: AACR–American Cancer Society Award for Research Excellence in Cancer Epidemiology or Prevention, sponsored jointly by the AACR and the American Cancer Society. Advancement of women in science: AACR–Women in Cancer Research–Charlotte Friend Memorial Lectureship, named for the renowned virologist and discoverer of the Friend virus, this lecture provides recognition for an outstanding scientist who has made meritorious contributions to the field of cancer research and who has, through leadership or by example, furthered the advancement of women in science. Advancement of minority investigators in cancer research: AACR-Minorities in Cancer Research-Jane Cooke Wright Lectureship, first presented in 2006, the lectureship is intended to give recognition to an outstanding scientist who has made meritorious contributions to the field of cancer research and who has, through leadership or by example, furthered the advancement of minority investigators in cancer research. Since 1961, when the first scientific award was presented, the AACR has honored hundreds of scientists and physicians, who collectively have made significant contributions to the understanding, diagnosis, prevention and treatment of cancer.